Computing the Distance between unbalanced Distributions -- The flat Metric

We provide an implementation to compute the flat metric in any dimension. The flat metric, also called dual bounded Lipschitz distance, generalizes the well-known Wasserstein distance W1 to the case that the distributions are of unequal total mass. This is of particular interest for unbalanced optimal transport tasks and for the analysis of data distributions where the sample size is important or normalization is not possible. The core of the method is based on a neural network to determine on optimal test function realizing the distance between two given measures. Special focus was put on achieving comparability of pairwise computed distances from independently trained networks. We tested the quality of the output in several experiments where ground truth was available as well as with simulated data

Seamless and Secure VR: Adapting and Evaluating Established Authentication Systems for Virtual Reality

Virtual reality (VR) headsets are enabling a wide range of new opportunities for the user. For example, in the near future users may be able to visit virtual shopping malls and virtually join international conferences. These and many other scenarios pose new questions with regards to privacy and security, in particular authentication of users within the virtual environment. As a first step towards seamless VR authentication, this paper investigates the direct transfer of well-established concepts (PIN, Android unlock patterns) into VR. In a pilot study (N = 5) and a lab study (N = 25), we adapted existing mechanisms and evaluated their usability and security for VR. The results indicate that both PINs and patterns are well suited for authentication in VR. We found that the usability of both methods matched the performance known from the physical world. In addition, the private visual channel makes authentication harder to observe, indicating that authentication in VR using traditional concepts already achieves a good balance in the trade-off between usability and security. The paper contributes to a better understanding of authentication within VR environments, by providing the first investigation of established authentication methods within VR, and presents the base layer for the design of future authentication schemes, which are used in VR environments only

Evaluating the performance of past climate model projections

Author Posting. © American Geophysical Union, 2020. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 47(1), (2020): e2019GL085378, doi:10.1029/2019GL085378.Retrospectively comparing future model projections to observations provides a robust and independent test of model skill. Here we analyze the performance of climate models published between 1970 and 2007 in projecting future global mean surface temperature (GMST) changes. Models are compared to observations based on both the change in GMST over time and the change in GMST over the change in external forcing. The latter approach accounts for mismatches in model forcings, a potential source of error in model projections independent of the accuracy of model physics. We find that climate models published over the past five decades were skillful in predicting subsequent GMST changes, with most models examined showing warming consistent with observations, particularly when mismatches between model‐projected and observationally estimated forcings were taken into account.Z. H. conceived the project, Z. H. and H. F. D. created the figures, and Z. H., H. F. D., T. A., and G. S. helped gather data and wrote the article text. A public GitHub repository with code used to analyze the data and generate figures and csv files containing the data shown in the figures is available online (https://github.com/hausfath/OldModels). Additional information on the code and data used in the analysis can be found in the supporting information. We would like to thank Piers Forster for providing the ensemble of observationally‐informed radiative forcing estimates. No dedicated funding from any of the authors supported this project.2020-06-0

Design Optimization of a 5 MW Floating Offshore Vertical-axis Wind Turbine

This paper outlines results of a proposed layout of a light 2-bladed rotor, with a driving torque constraint matching the generator design, and shows details of the pultruded blade – and rotor geometry. In comparison with the 1st baseline design of a 5 MW VAWT concept this present development provides during standstill and operation significant less mass with a comparable level of loading strain in the blades and in the junctions between blade and tower. Optimized blade profile having a low weight and high stiffness is obtained according to the design evaluations based on the standstill calculations in ANSYS software. The selected profiles are used in the aero dynamic simulation. Furthermore the simulation code will be demonstrated to show the fully development model, integrating the simulation of turbulent wind inflow, actuator cylinder flow model, power controls, hydraulic floater - and mooring line systems implementation

High (but Not Low) Urinary Iodine Excretion Is Predicted by Iodine Excretion Levels from Five Years Ago

Background: It has not been investigated whether there are associations between urinary iodine (UI) excretion measurements some years apart, nor whether such an association remains after adjustment for nutritional habits. The aim of the present study was to investigate the relation between iodine-creatinine ratio (ICR) at two measuring points 5 years apart. Methods: Data from 2,659 individuals from the Study of Health in Pomerania were analyzed. Analysis of covariance and Poisson regressions were used to associate baseline with follow-up ICR. Results: Baseline ICR was associated with follow-up ICR. Particularly, baseline ICR >300 mu g/g was related to an ICR >300 mu g/g at follow-up (relative risk, RR: 2.20; p < 0.001). The association was stronger in males (RR: 2.64; p < 0.001) than in females (RR: 1.64; p = 0.007). In contrast, baseline ICR <100 mu g/g was only associated with an ICR <100 mu g/g at follow-up in males when considering unadjusted ICR. Conclusions: We detected only a weak correlation with respect to low ICR. Studies assessing iodine status in a population should take into account that an individual with a low UI excretion in one measurement is not necessarily permanently iodine deficient. On the other hand, current high ICR could have been predicted by high ICR 5 years ago. Copyright (C) 2011 S. Karger AG, Base

Clinical and Serological Characterization of Orf-Induced Immunobullous Disease

Importance: Ecthyma contagiosum, or orf, is a viral zoonotic infection caused by Poxviridae. Although human orf infection is considered to follow a self-limited course, various immunological reactions may be triggered, including immunobullous diseases. In the majority of the latter cases, the antigenic target remained enigmatic. Objective: To characterize the predominant autoantigen in orf-induced immunobullous disease and further describe this clinical entity. Design, Setting, and Participants: This multicenter case series sought to provide detailed clinical, histopathological and immunological characteristics of a patient with orf-induced pemphigoid. Based on this index patient, serological analyses were conducted of 4 additional patients with previously reported orf-induced immunobullous disease. Immunoblotting with extracellular matrix and a recently established indirect immunofluorescence assay for detection of serum anti-laminin 332 IgG were performed. Exposures: The disease course and clinical characteristics of orf-induced immunobullous disease were observed. Main Outcomes and Measures: Orf-induced immunobullous disease is primarily characterized by anti-laminin 332 autoantibodies, predominant skin involvement, and a self-limiting course. The study provides further details on epidemiological, clinical, immunopathological, diagnostic, and therapeutic aspects of orf-induced immunobullous disease. Results: In all 5 patients, IgG1 and/or IgG3 autoantibodies against laminin 332 were identified. The α3, β3, and γ2 chains were recognized in 2, 4, and 1 patient(s), respectively. Conclusions and Relevance: In this case series, laminin 332, a well-known target antigen in mucous membrane pemphigoid, was a major autoantigen in orf-induced immunobullous disease, even though predominant mucosal lesions were lacking in this autoimmune blistering disease. Orf-induced anti-laminin 332 pemphigoid is proposed as distinct clinical entity